A B C

Zeitschrift für Naturforschung B Contents Vol. 69b (2014)

Z. Naturforsch. 2014, 69b, 519 – 524

doi:10.5560/ZNB.2014-4053

Orthoamides and Iminium Salts LXXXVII [1]. A New and Facile Synthesis of 1,3-Dimethylthymine

Orthoamide und Iminiumsalze, LXXXVII [1]. Eine neue, einfache Synthese für 1,3-Dimethylthymin

Willi Kantlehner^1,2, Jochen Mezger¹ and Ivo C. Ivanov¹

¹Fakultät Chemie/Organische Chemie, Hochschule Aalen, Beethovenstr. 1, D-73430 Aalen, Germany

²Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany

Reprint requests to Prof. Dr. Willi Kantlehner. Fax: +49(7361)5762250. E-mail: willi.kantlehner@htw-aalen.de

Received March 4, 2014 / published online May 7, 2014

Dedicated to Professor Gerhard Maas on the occasion of his 65^th birthday

1,3-Dimethylthymine can be prepared in a single-step reaction by heating a mixture of N-methyl-propionamide and the Bredereck-Simchen reagent [tert-butyloxy-bis(dimethylamino) methane].

Key words: Nucleo Base, Thymine, Bredereck-Simchen Reagent [tert-Butoxy-bis(dimethylamino)methane]

Full-text PDF