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Z. Naturforsch. 2014,
69b, 1021 – 1025
doi:10.5560/ZNB.2014-4114
The Structure Elucidation and Antimicrobial Activities of Nonsterol Triterpenoids from Ixeris chinensis
College of Traditional Mongolian Medicine, Inner Mongolia University for Nationalities, No. 536 Hulinhe District, Tongliao 028000, P. R. China
Reprint requests to Prof. Qing-Hu Wang. Fax: +86-0475-8314242. E-mail:
wqh196812@163.com
Received May 29, 2014 / published online October 12, 2014
An investigation of the petroleum ether extract from Ixeris chinensis Nakai has led to the isolation of a new compound, 3-O-acetyl-22,28-cyclobauer-7-en-3β-ol (1), together with four known compounds which have been isolated from this plant for the first time, namely taraxast-20-en-3β-ol (2), 3-O-acetyl-taraxast-20-en-3β-ol (3), taraxast-20(30)-en-3β-ol (4), and 3-O-acetyl-taraxast-20(30)-en-3β-ol (5). The structures of the isolated compounds have been elucidated on the basis of spectroscopic methods including UV, IR, ESI-MS, 1D NMR, 2D NMR techniques, and by comparison with data reported in the literature. All compounds have been evaluated for their activity against various bacteria and shown to give good results.
Key words: Ixeris chinensis Nakai, Nonsterol Triterpenoids, Antimicrobial Activity, 3-O-Acetyl-22,28-cyclobauer-7-en-3β-ol