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Z. Naturforsch. 2014, 69b, 439 – 443
doi:10.5560/ZNB.2014-3318
Reaction of N-Methylimidazole and Dimethyl Acetylenedicarboxylate in the Presence of N-Phenyl Carbamate under Solvent-free Conditions
Rahimeh Hajinasiri and Halimeh Khatoon Khajavi
Chemistry Department, Qaemshahr Branch, Islamic Azad University, Qaemshahr, I. R. Iran
Reprint requests to Dr. Rahimeh Hajinasiri. Fax: +981232240091. Tel: +981232145117. E-mail: rhmhajinasiri@yahoo.com
Received November 28, 2013 / published online April 7, 2014
An efficient synthesis of 1,2,3-functionalized imidazoles and dimethyl-2-[(alkoxycarbonyl)anilino]-2-butenedioate derivatives via one-pot reactions between N-methylimidazole, dimethyl acetylenedicarboxylate and N-phenylcarbamates under solvent-free conditions is described. The mild reaction conditions and good yields exhibit the synthetic advantage of this method.
Key words: N-Methylimidazole, Solvent-free, N-Phenylcarbamate 1,2,3-Functionalized Imidazoles
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