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Z. Naturforsch. 2013,
68b, 1129 – 1137
doi:10.5560/ZNB.2013-3196
Surface-active Ionic Liquids for Micellar Extraction of Piperine from Black Pepper
1 Institute of Applied Synthetic Chemistry, Vienna University of Technology, 1060 Vienna, Austria
2 Group for Biologically Inspired Materials, Institute of Nanobiotechnology (DNBT), University of Natural Resources and Life Sciences, Muthgasse 11, 1190 Vienna, Austria
Reprint requests to Dr. K. Bica. Fax: +43 1 58801 16399. E-mail:
katharina.bica@tuwien.ac.at
Received July 23, 2013 / published online October 4, 2013
We present the application of ionic liquid-aqueous micellar solutions as isolation media for the pharmaceutically active ingredient piperine from black pepper. Several surface-active ionic liquids including a biodegradable betaine derivative were used for the extraction of piperine, and a strong correlation between extraction yield and the critical micelle concentration of the respective ionic liquid was found. A scaled strategy for the isolation of piperine was developed that allowed recovery and recycling of the aqueous ionic liquid micellar solution for five runs without any loss in extraction efficiency.
Key words: Ionic Liquids, Micelles, Active Ingredient Isolation, Piperine, Biomass Processing, Sustainable Chemistry