A B C
Z. Naturforsch. 2013, 68b, 289 – 292
doi:10.5560/ZNB.2013-3014
A Polyketide Metabolite from an Endophytic Fusarium equiseti in a Medicinal Plant
Yoshihito Shiono1, Fumiaki Shibuya1, Tetsuya Murayama1, Takuya Koseki1, Herve Martial Poumale Poumale2, and Bonaventure Tchaleu Ngadjui2
1 Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata 997-8555, Japan
2 Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, P. O. Box 812, Yaoundé, Cameroon
Reprint requests to Prof. Yoshihito Shiono. Tel./Fax: +81-235-28-2873. E-mail: yshiono@tds1.tr.yamagata-u.ac.jp
Received January 16, 2013 / published online March 20, 2013
A new polyketide, fusaequisin A (1), was isolated from rice cultures of Fusarium equiseti SF-3-17, an endophytic fungus previously discovered during screening of medicinal plants in Cameroon. The structure of 1 was determined using spectroscopic methods. Fusaequisin A (1) exhibited moderate antimicrobial activity against Staphylococcus aureus NBRC 13276 and Pseudomonas aeruginosa ATCC 15442 at a concentration of 200 μg per disk.
Key words: Endophyte, Fusarium equiseti, Antimicrobial Activity
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