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Z. Naturforsch. 2013,
68b, 175 – 181
doi:10.5560/ZNB.2013-2252
Studies with Enamines: Route to Aminoazolopyrimidines and Arylazoazolopyrimidines
Department of Chemistry, College of Applied Sciences, Umm AlQura University, P. O. Box 13401, Makkah 21955, Saudi Arabia
Reprint requests to Dr. A. M. Salaheldin. E-mail:
amsalaheldin@yahoo.com.
Received September 5, 2012 / published online February 20, 2013
An easy preparation of enaminonitrile derivatives and their transformation into new substituted azolopyrimidines is described. The one-step transformation was carried out under microwave irradiation and by classical heating methods. The use of microwave irradiation led to high conversion and shorter reaction times.
Key words: Azolopyrimidines, Enamines, Azoloazines, Microwave Irradiation